Rachel McAdams Pictures: Rachel McAdams arrives on the red carpet at the world premiere of "Sherlock Holmes" held at Empire Leicester Square on December 14, 2009 in London, England.
Robert Downey Jr. brings the legendary detective to life as he has never been portrayed before. Jude Law stars as Holmes' trusted colleague, Watson, a doctor and war veteran who is a formidable ally for Sherlock Holmes. Rachel McAdams stars as Irene Adler, the only woman ever to have bested Holmes and who has maintained a tempestuous relationship with the detective. Mark Strong stars as their mysterious new adversary, Blackwood. Kelly Reilly will play Watson's love interest, Mary.